A couple of days before 1899 Christmas, the Oxford new graduate Dr. Edward Newgate arrives at the Stonehearst Asylum to complete training for his specialty of asylum medicine. He is met by armed men who take him to Dr. Silas Lamb, who welcomes his help and takes him under his wing. Edward is shocked to see the methods that Dr Lamb uses to run this asylum. He becomes infatuated with Eliza Graves, one of the patients who is a lady of status and does not seem to belong. One night, Edward overhears a knocking from the bowels of the facility and is shocked to find that everything is not as it seems in this place and that his uneasy feelings may be justified. What will Edward Choose?